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It was pointed out in Opinions on Promoting the Inheritance, Innovation and Development of Traditional Chinese Medicine issued by the State Council in 2019 that 100 varieties of traditional Chinese medicine(TCM) with unique curative effects should be screened out within about three years. Due to the multi-component and multi-target mechanisms of TCM varieties, it is difficult to directly and simply evaluate their multi-dimensional clinical value using methods applicable to chemical or biological agents. The heterogeneity of outcomes for similar TCM makes it difficult to determine the advantages of similar products. The fuzzy comprehensive evaluation method that is developed on the basis of core outcome set and fuzzy mathematics for clinical efficacy evaluation of TCM may solve these problems. This study developed a fuzzy comprehensive evaluation model for the clinical efficacy evaluation of Chinese patent me-dicines for coronary heart disease and angina pectoris, and selected the previous normative studies with complete or incomplete data for verifying the model application. The results showed that original studies with complete data failed to evaluate and compare the comprehensive efficacy of different interventions. The original research only mentioned the advantages and disadvantages of different interventions in different aspects. The comprehensive clinical efficacy of three different interventions obtained through fuzzy comprehensive evaluation was all graded as level Ⅱ. The original research with incomplete data drew the same conclusions as the fuzzy comprehensive evaluation, and the results of fuzzy comprehensive evaluation can provide more comprehensive information. Therefore, the fuzzy comprehensive evaluation shows the products with overall advantages of clinical efficacy, which may become a feasible method for the screening of TCM.
Subject(s)
Humans , Angina Pectoris , Coronary Disease/drug therapy , Drugs, Chinese Herbal/therapeutic use , Medicine, Chinese Traditional , Treatment OutcomeABSTRACT
【Objective】 To establish the quantitative classification model of blood inventory warning for public health emergencies, so as to provide reference for practical application. 【Methods】 The classification model of blood inventory early warning for public health emergencies was constructed through literature review, fuzzy comprehensive evaluation method and analytic hierarchy process (AHP). The constructed model was used to conduct fuzzy comprehensive evaluation on the data of day 10 before, day 1/5/40 after the launch of Level I public health event response in Deyang Central Blood Station in 2020 and calculate the warning level. 【Results】 The warning levels of day 10 before, and day 1/5/40 after the response were blue, orange, red and blue, respectively, which were consistent with the actual situation of Deyang performing Level I public health event response at that time. 【Conclusion】 It is feasible to use fuzzy comprehensive evaluation method to build the blood inventory warning classification model in public health emergency, which provides theoretical reference for practical application.
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Objective To establish a scientific and objective evaluation model of the comprehensive performance of immunocolloidal gold qualitative rapid detection kits, and to provide a reference for the overall evaluation of similar products. Methods Based on the various factors affecting the performance of qualitative rapid detection kits, a comprehensive performance evaluation index system consisting of 4 first-level indicators and 18 second-level indicators was constructed.The analytic hierarchy process (AHP) and the fuzzy comprehensive evaluation (FCE) method were combined to determine the weights for the evaluation indicators and graded thresholds.The model was then used to evaluate the performance level of 6 brands of furazolidone metabolite rapid test kits. Results According to maximum membership degree principle, the evaluation of brand A, B, C, D, E and F were graded as good, excellent, middle, excellent, middle and excellent, respectively.Then the scores of 6 brands were calculated according to the hundred-mark system, and brand B had the highest score.This was consistent with the actual use experience. Conclusion The application of this model can make the evaluation results more comprehensive and accurate, providing reference for rational evaluation and selection of qualitative rapid detection kits.
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Objective: To explore the optimal configuration methods of medical equipment of hospital so as to increase the scientific, rationality, fairness and effectiveness of decisions for equipment configuration of hospital. Methods:The applications of ultrasound imaging equipment configuration of two departments were used as example. Through a series of steps, included establishing the hierarchical structure of model, constructing the judgment matrix, consistency check, determining the weight matrix, determining the evaluation set and fuzzy evaluation matrix, and calculating the evaluation vector quantity and so on, the fuzzy comprehensive evaluation model was performed and applied in the evaluation of equipment configuration. Results: After evaluation, for the ultrasound imaging equipment configuration of department 1, the ratio of experts who thought the introduction of this equipment was very good was 82.92%, and the ratio of experts who thought it was better was 12.36%, and the ratio of experts who though it was normal was 4.72%. While for department 2, the ration of experts who though it was normal or worst was more than 50%. Conclusion:The fuzzy comprehensive evaluation model is an effective method for verifying equipment configuration. It can provide effective and quantitative assessment results for decision makers of hospital and provide reference for optimal configuration of medical equipment of hospital.
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Objective To explore the application of fuzzy mathematics theory in the evaluation of medical students' comprehensive mental quality. Methods A total of 80 medical undergraduates studying in the Affiliated Huai'an No.1 People’s Hospital of Nanjing Medical University from October to December 2017 were randomly selected to conduct a questionnaire survey on medical students' mental quality. The questionnaires were designed by the study group, containing 3 first-level items (learning pressure, life stress and interpersonal stress), and 19 secondary items, with the recovery rate as 95%. Fuzzy comprehensive evaluation method was used for data processing and analysis. Results By comparing the data obtained from the comprehensive evaluation of the secondary factors with those of the pre-set evaluation set, the study concluded that 25.00% of the medical students need to adjust the future pressure, 41.70% the family health status pressure and 26.79% the appearance pressure according to the principle of maximum mem-bership degree. The comprehensive evaluation of the first four factors (0.249 7, 0.268 9, 0.270 2, and 0.211 2) showed that the comprehensive mental quality of medical students was "good". The quantitative analysis results showed that 27.02% of the medical students had good comprehensive mental quality, 24.97% need the mental quality adjustments, 26.89% had the average mental quality, and 21.12% had outstanding mental quality. Fuzzy comprehensive evaluation indicated that it is necessary to adjust the learning pressure and life stress of medical students, while the interpersonal stress had little effect on the mental quality of medical students. Conclusion The fuzzy comprehensive evaluation adopts the quantitative method to deal with the qualitative indicators uniformly, being scientific and reasonable. The corresponding data of each indicator can be easily identified with the help of the indicator system built up in the evaluation, which provides evidence for distinguishing and improving the corresponding decision-making for improving the medical students' mental quality. This evaluation method has strong applicability and provides new methods and ideas for objectively evaluating the comprehensive mental quality of medical students.
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Objective To quantify the results of the assessment of verbal communication ability in old people,to establish a graded nurs-ing service for the senior.Methods From March,2016 to May,2017,50 old volunteers in the nursing home and hospital were assessed the verbal communication ability with language barrier diagnosis and treatment apparatus ZM2.1.The indexes were analyzed with a fuzzy com-prehensive and principal component quantitative analysis model,to grade the verbal communicative ability.The results were compared with that of the clinic.Results Two principal components were extracted,with the variance contribution rates of 77.53% and 14.12%,and was cu-mulative to 91.65%.The consistency was not less than 80% from the results of the clinical assessment.Conclusion It is feasible to quantify the verbal communication ability in the old people with fuzzy principal component analysis.
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Objective To establish a method to evaluate quality of Angelicae Sinensis Radix based on analytic hierarchy process (AHP) fuzzy comprehensive evaluation. Methods Angelicae Sinensis Radix of different producing regions was collected. Volatile oil content, alcohol soluble extract content, as well as the composition of ferulic acid, Z-ligustilide, 3-butylphthalide and n-butylidenephthalide of Angelicae Sinensis Radix samples were separately measured. AHP was used to establish AHP analysis model to comprehensively evaluate multiple indexes of Angelicae Sinensis Radix. Results The evaluation result comparison showed that the quality of Angelicae Sinensis Radix in Min county, Weiyuan county and Zhang county were better than that of other regions, and Min county had the Angelicae Sinensis Radix with the best quality. Conclusion Evaluating Angelicae Sinensis Radix based on AHP fuzzy comprehensive evaluation model is feasible.
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Objective Risk management is one of the strong measurements to ensure the conduction of new drug research and development (R&D) projects .Therefore ,establishing a set of evaluation index system in the new drug R&D projects is of great significance to increase the project success rate .Methods By analyzing more than 20 new drug R&D projects of “the mil-itary science and technology major projects”in five years ,the risk factors were induced ,sorted and summed up ,and a set of e-valuation indicator was built up through Delphi method and experts interview .The quantitative study was completed through fuzzy comprehensive evaluation method .Results According to the different stages of new drug R&D projects ,the risk assess-ment indictors and their weight were established .Conclusion These indicators are more objective and accurate which contrib-ute to the risk control in the process of new drug R&D projects .
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Objective To explore an objective evaluation model for the elderly extremity muscle strength. Methods Evaluation index system of extremity muscle strength was established by analyzing the structure and movement mechanism of the limbs of the elderly,and an evaluation model of extremity muscle strength of the elderly based on entropy weight-fuzzy comprehensive evaluation was proposed.More-over,the muscle strength data of the elderly are collected by the hand-held dynamometry MicroFet3.Results The entropy weight method was used to obtain the objective weight of each index,and the disadvantages of the given weight by the expert in the fuzzy comprehensive evaluation method were eliminated, which could effectively assist the doctor to give the correct evaluation. Conclusion Actual examples showed that the proposed evaluation model is effective and objective,which helps to overcome the subjectivity of manual muscle testing to achieve the rehabilitation treatment and classification management of the elderly.A new idea is put forward to evaluate the strength of the ex-tremity in the elderly.
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The paper builds the evaluation index system of university library self-built database service performance through Analytic Hierarchy Process (AHP),introduces the building principle,hierarchical structure and index weight,and evaluates the self-built database service performance of the library of Yunnan University of Traditional Chinese Medicine through Fuzzy Comprehensive Evaluation (FCE) based on this evaluation system.The evaluation result is basically consistent with the actual situation,which verifies the scientificity and operability of this index system.
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OBJECTIVE:To explore the problems and improvement measures in the process of operation and management of B2C pharmaceutical E-commerce enterprise,and to promote their development. METHODS:The performance evaluation index sys-tem was built preliminarily,including 5 first-level indexes and 28 second-level indexes. Questionnaires survey was conducted among 16 experts by Delphi method,and the weight of every index was calculated by experts according to importance,familiarity and reference. The company performance was analyzed and judged objectively by fuzzy comprehensive evaluation method. The re-sults of Y enterprise performance evaluation were empirically analyzed. RESULTS & CONCLUSIONS:The performance evaluation index system has been built,including 5 first-level indexes,24 second-level indexes. Average expert authority degree of two rounds survey is 0.76(>0.70),showing survey result is credible. The performance of the company in the finance and popularization have more influence to the performance of B2C pharmaceutical E-commerce enterprise. The performance of Y company is outstanding in profit growth,site stability and security,suppliers development and maintain and other aspects;however,it is not good enough of performance in employee satisfaction,customer professional services,logistics and distribution quality and other aspects. It is sug-gested to establish logistics by B2C pharmaceutical E-commerce enterprise themselves,carry out whole-course monitoring to im-prove the quality of logistics and distribution;increase product and pharmaceutical knowledge training input and introduce talent with the background of medical education so as to strengthen professional service;survey the satisfactory degree of staff to working environment,working group,working content and other aspects,and adjust enterprise system or communicate with staff in order to improve satisfactory degree.
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Objective To evaluate sanitary quality of drinking water of small centralized water supply in rural areas using fuzzy comprehensive evaluation method.Methods Fifteen rural small centralized water supply facilities in Jinhua City were randomly selected.The health -related indicators were detected,and fuzzy comprehensive evaluation was used to evaluate the test results.Results The qualification rate of fifteen rural small centralized water supply facilities detected was 6. 67%.The qualified rate of the heat-resistant coliform bacteria in all items was 26. 67%,and the qualified rate of total coliforms was 6. 67%.The qualified rate of total numbers of colony,fluorid,chloride,sulfate,total dissolved solids, iron,oxygen consumption,total hardness and nitrate was all 1 00%.Sanitary quality of the water supply facilities was judged by the fuzzy membership evaluation.There were 4 water supply facilities evaluated as level Ⅰ(good),level Ⅱ(qualified ) and level Ⅳ (bad ) respectivley,and 3 water supply facilities evaluated as level Ⅲ (poor ).Fuzzy comprehensive index of sanitary quality was less than 0. 5 .Conclusion There is a risk of security in rural small centralized water supply water of Jinhua City.The low qualified rate of rural small centralized water supply water was due to heat-resistant coliform bacteria and total coliforms.The relevant departments should strengthen the hygiene management. Disinfection equipment should be installed,and standardized disinfection should be promoted to improve water quality.
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Objective To assess the hygienic status of the central air conditioning ventilation system in public places by fuzzy comprehensive evaluation method.Methods According to the comprehensive evaluation method of public place (WS /T 199—2001),a fuzzy comprehensive evaluation method was applied to evaluate central air conditioning ventilation systems in 15 large public places of Jinhua City.Results The qualified rate of central air ventilation system was 53.30%, and the qualified rates of total number of bacteria,the fungi,β-hemolytic streptococcus in air blow and Legionella bacteria in the cooling water all reached 100.00%.At the same time,the qualified rate of bacteria,fungi and dust volume in internal surface of pipe were 93.33%,86.67% and 80.00% respectively.The qualified rate of PM10 was 86.67%. Among 15 central air conditioning ventilation systems,13 systems were evaluated as level Ⅰ,and the other two was as level Ⅱand Ⅳ respectively.TAAlso,14 evaluated units got the fuzzy comprehensive indexes of central air ventilation less than 0.5.Conclusion The hygiene status of central air conditioning ventilation system in Jinhua is acceptable,and the management of hygiene quality should be strengthened.
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OBJECTIVE:To investigate the application of fuzzy comprehensive evaluation in formulation screening. METH-ODS:Taking Compound paracetamol and chlorphenamine maleate granules as model drug,based on single factor experiment,L9(34) orthogonal test was used to screen the formulation with the amount of aspartame,hawthorn powder essence,milk powder essence and saccharose as factors,using dissolution rate of caffeine as index. The granules prepared by 9 kinds of formulation in orthogonal test were evaluated with fuzzy comprehensive evaluation in terms of taste,aroma,color and dissolubility. The optimized formula-tion was validated and compared with original formulation. RESULTS:The formulation 5 was the optimal choice in both orthogo-nal test and fuzzy comprehensive evaluation,and obtained same results. Compared with sensory comprehensive score (63.12) and dissolution rate of caffeine (91.3%) in original formulation,two indicators of optimized formulation in 3 tests were 84.00 and 99.07% in average (RSD<2.0%,n=3). CONCLUSIONS:Fuzzy comprehensive evaluation can be used for the formulation screening of sensory evaluation index. It is scientific and accurate.
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Objective:To understand the responsiveness of community health service institutions in Henan Province. Methods:This research collected information through questionnaire investigations. The object of the investigations is key informants familiar with community health service institutions. Various dimensions of responsiveness within Henan province community health service institutions are determined through a multiple-input pecking order graph. The fuzzy comprehen-sive evaluation method is used to evaluate the level of responsiveness. Responsiveness inequality index is used to measure the distribution of reactions. Results:A total of 431 valid key informants were surveyed. The various dimensions of the questionnaire of Cronbach alpha coefficient was greater than 0. 623;the total scale of the Cronbach alpha coefficient was 0. 850;the correlation coefficient of each dimension of test-retest reliability were greater than 0. 907. The levels of responsive-ness and distribution index were 8. 33 and 0. 2744, respectively;each dimension by order of importance:timely attention>dignity>infrastructure>communication>confidentiality >social support >selective >autonomy. Approximately 50% of key informants considered that vulnerable groups in community health service institutions were sometimes or often treated unfairly. Conclusion:Key informants considered the responsiveness level of overall higher community health service institu-tions in Henan Province was high, and the distribution of responsiveness was relative equilibrium. However, there is a large shortage of infrastructure, privacy protection, doctor-patient communication, etc.
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In observance of the comprehensive,scientific,quantitative and qualitative principles of performance evaluation,the performance evaluation process and evaluation index system for TUMC Tumor Building Project is put in place.The evaluation index system has three dimensions,project decision-making,project management and project performance,and 20 qualitative indicators such as project output ratio,and socio-economic effect.The fuzzy comprehensive evaluation method was called into play for an objective evaluation.Success of TUMC Tumor Building Project proved the efficiency of project management in decision-making and construction management.
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Objective To use fuzzy comprehensive evaluation method for rationally evaluating the performance of military hospitals. Methods The performance of a military hospital (2009-2011) was evaluated from the following four domains: patient, finance, internal flow, and learning and growth. Multi-layer fuzzy comprehensive evaluation method was used to obtain the fuzzy membership of all the domains of the subjects, and the evaluation results were subjected to corresponding analysis. Results It was found that the total proportion of "good" and "comparatively good" performance was 76.85% for a military hospital in 2009-2011. The overall performance degree of the hospital was "good" according to the maximal fuzzy membership principle. And corresponding analysis showed that the result was "moderate" for the financial domain, "poor" or "comparatively poor" for the patient domain, "good" for the internal flow domain, and "good" or "comparatively good" for the learning and growth domain. Conclusion Multi-layer fuzzy comprehensive evaluation method can properly handle the problem of multiple parameter integration in a system, and corresponding analysis makes the evaluation results more rational and more objective.
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Objective To judge the hospital crisis and to provide the approaches and strategies to avoid the hospital crisis. Methods To conduct specific diagnosis of important risk factors of hospitals using expert diagnostics and crisis identification. Results Combined with the index system and weight affecting public hospitals' crisis, to focus on preventing risk factors directly, which had severe affection and put great weight on hospital crisis. To raise up the containments, managing strategies and mechanisms for public hospitals' crisis. Conclusions It is an effective method to warn and prevent hospital crisis by the way of establishing public hospital crisis value with fuzzy comprehensive evaluation system.
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Objective To learn the organizational management competency of state-owned hospitals and their weakness, providing references for decision makers. Methods In the principle of stratified random sampling, 5 677 doctors in hospitals of different grades from 12 cities in Shandong Province, Hubei Province, Hebei Province and Inner Mongolia were investigated with questionnaires. Factor analysis is applied to extract factors. With results of this factor analysis, an evaluation model was built, followed by a fuzzy comprehensive evaluation on the management competency. Results The total satisfaction score on the organizational management by the doctors investigated is 3. 25, and those for system building and leadership behavior are respectively 2.88 and 3.20. Conclusions Organizational management of the public hospitals needs improving, especially development of hospital management systems and implementation.
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The ergonomics of equipment is important,it is essential to make the ergonomic evaluation in the stage of design. The operation of expanded shelter is a typical form of combination of human labor and machine. The fuzzy comprehensive evaluation model is founded. The high-level factor set include the states of operation, the ratio of every state time to the total time is the corresponding weight for the elements in high-level factor set, the lower-level factor set include the elements which influence the states of operation. For the elements in lower-level factor set, the corresponding weight is given by the experts.